Spots over Dogs' Eyes

Indolent ulcers in dogs’ eyes

Corneal ulcers are probably the most common problem of the canine eye seen in general veterinary practice. Most of these ulcers result from a variety of traumatic and irritating conditions and usually respond well to medical therapy alone, provided they are not too deep. However, indolent ulcers are different: they are chronic superficial ulcers that result from a structural defect of the corne...

What’s Hot, with Spots and Red All Over? Murine Typhus

A 17-year-old male presented to the emergency department with complaints of fever, rash that originated on the abdomen, malaise, and a cough for 10 days prior to evaluation. The patient reported an encounter with an opossum three days prior to the onset of symptoms. Vital signs were a temperature of 101.2°F, a heart rate of 129 beats per minute, 12 respirations per minute and a blood pressure o...

The microperimetry of resolved cotton-wool spots in eyes of patients with hypertension and diabetes mellitus.

BACKGROUND Retinal cotton-wool spots (CWSs) are an important manifestation of retinovascular disease in hypertension (HTN) and diabetes mellitus (DM). Conventional automated perimetry data have suggested relative scotomas in resolved CWSs; however, this has not been well delineated using microperimetry. This study evaluates the retinal sensitivity in documented resolved CWSs using microperimetr...

Terminal sedation: pulling the sheet over our eyes.

Spots

Fas (CD95, APO-1, TNFRSF6) is a TNF receptor superfamily member that directly triggers apoptosis and contributes to the maintenance of lymphocyte homeostasis and prevention of autoimmunity. Although FADD and caspase-8 have been identified as key intracellular mediators of Fas signaling, it is not clear how recruitment of these proteins to the Fas death domain leads to activation of caspase-8 in...